While each ARCHICAD project has only one Layer set, the settings of any particular layer (for example its show/hide or locked/unlocked status) can be different in the Layout Book and in Model Views. The settings variation you see in the Layer Settings Dialog Box (either Layout Book or Model Views) depends on which window is active when you open Layer Settings. Both the Layer Settings command and the dialog box are labeled accordingly.
Important: Layer settings for the Layout Book serve to show/hide elements directly placed on layouts, such as lines, texts and drawings as a whole. Layout Book layers do not affect the drawing content, which is determined by the layers of its associated view.